🫀 Liver Function

GGT: What It Means for Your Health

GGT (gamma-glutamyl transferase) is an enzyme found in many tissues but is most concentrated in the liver and bile ducts. It is one of the most sensitive markers of liver disease and is particularly useful for detecting alcohol-related liver damage and bile duct obstruction. GGT is often used alongside ALP to determine whether an elevated ALP originates from the liver (if GGT is also elevated) or from bone (if GGT is normal).

Full Name
Gamma-Glutamyl Transferase (GGT)
Normal Range
0–55 U/L
Also Known As
Gamma GT, Gamma-Glutamyl Transferase

Reference Range

LowNormal: 0–55 U/LHigh

Reference ranges may vary between laboratories, age groups, and sexes. The values shown are general adult reference ranges. Always compare your results to the specific range provided by your testing laboratory.

What Is GGT?

GGT (gamma-glutamyl transferase) is an enzyme found in many tissues but is most concentrated in the liver and bile ducts. It is one of the most sensitive markers of liver disease and is particularly useful for detecting alcohol-related liver damage and bile duct obstruction. GGT is often used alongside ALP to determine whether an elevated ALP originates from the liver (if GGT is also elevated) or from bone (if GGT is normal).

Commonly included in:

Liver Function PanelHepatic Panel

What Does High GGT Mean?

Above 55 U/L

Elevated GGT is commonly caused by alcohol consumption (even moderate amounts), bile duct obstruction, fatty liver disease, hepatitis, cirrhosis, pancreatitis, heart failure, certain medications (phenytoin, barbiturates), and diabetes. GGT is the most sensitive enzymatic marker of alcohol use. Elevated GGT has also been linked to increased cardiovascular disease risk.

What Does Low GGT Mean?

Below 0 U/L

Low GGT is generally normal and not clinically significant. It may be seen with hypothyroidism.

Related Biomarkers in Liver Function

ALT
Liver enzyme primarily found in liver cells — the most specific marker of liver damage.
Range: 0–41 U/L
AST
Enzyme found in liver, heart, and muscle — rises with tissue damage.
Range: 0–40 U/L
ALP
Enzyme found in liver, bone, kidneys, and intestines.
Range: 44–147 U/L
Total Bilirubin
Yellow pigment from red blood cell breakdown processed by the liver.
Range: 0.1–1.2 mg/dL
Albumin
Most abundant blood protein, made by the liver, essential for fluid balance.
Range: 3.5–5.5 g/dL

Track Your GGT Over Time

Upload your blood test results to Hemoly and see how your GGT levels change over time. Get trend analysis, educational insights, and a personal health timeline.

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Medical Disclaimer

This information is for educational purposes only and is not intended as medical advice, diagnosis, or treatment. Reference ranges may vary between laboratories. Always consult a qualified healthcare professional for interpretation of your blood test results and before making any health decisions.