Magnesium: What It Means for Your Health
Magnesium is involved in more than 300 enzymatic reactions, including energy production, DNA synthesis, muscle relaxation, nerve function, and blood sugar regulation. About 60% is stored in bones, 39% in muscles and soft tissues, and only 1% circulates in blood. This means serum magnesium can be normal even when total body stores are depleted, making deficiency notoriously difficult to diagnose by blood tests alone.
Reference Range
Reference ranges may vary between laboratories, age groups, and sexes. The values shown are general adult reference ranges. Always compare your results to the specific range provided by your testing laboratory.
What Is Magnesium?
Magnesium is involved in more than 300 enzymatic reactions, including energy production, DNA synthesis, muscle relaxation, nerve function, and blood sugar regulation. About 60% is stored in bones, 39% in muscles and soft tissues, and only 1% circulates in blood. This means serum magnesium can be normal even when total body stores are depleted, making deficiency notoriously difficult to diagnose by blood tests alone.
Commonly included in:
What Does High Magnesium Mean?
Elevated magnesium (hypermagnesemia) is uncommon and usually occurs in kidney failure (reduced excretion) or excessive magnesium supplementation/antacids. Symptoms include nausea, facial flushing, muscle weakness, low blood pressure, and in severe cases, respiratory depression and cardiac arrest.
What Does Low Magnesium Mean?
Low magnesium (hypomagnesemia) is common and underdiagnosed, affecting up to 15% of the general population. Causes include poor dietary intake, chronic alcohol use, diabetes, malabsorption, diuretics, and proton pump inhibitors. Symptoms include muscle cramps, tremors, fatigue, irritability, and cardiac arrhythmias. Low magnesium also impairs calcium and potassium regulation.
Related Biomarkers in Electrolytes & Minerals
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This information is for educational purposes only and is not intended as medical advice, diagnosis, or treatment. Reference ranges may vary between laboratories. Always consult a qualified healthcare professional for interpretation of your blood test results and before making any health decisions.